Results 131 to 140 of about 1,050,552 (339)
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Computer graphics for management: An abstract of capabilities and applications of the EIS system [PDF]
The Executive Information Services (EIS) system, developed as a computer-based, time-sharing tool for making and implementing management decisions, and including computer graphics capabilities, was described. The following resources are available through
Solem, B. J.
core +1 more source
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
TikZero: Zero-Shot Text-Guided Graphics Program Synthesis [PDF]
With the rise of generative AI, synthesizing figures from text captions becomes a compelling application. However, achieving high geometric precision and editability requires representing figures as graphics programs in languages like TikZ, and aligned training data (i.e., graphics programs with captions) remains scarce.
arxiv
Computer Graphics And Image Processing Laboratory For Undergraduate Instruction [PDF]
D. Mikkelson
openalex +1 more source
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain+3 more
wiley +1 more source
DETECTING DIGITAL IMAGE FORGERIES USING RE-SAMPLING BY AUTOMATIC REGION OF INTEREST (ROI) [PDF]
Nowadays, digital images can be easily altered by using high-performance computers, sophisticated photo-editing, computer graphics software, etc. It will affect the authenticity of images in law, politics, the media, and business.
P. Subathra, A. Baskar, D. Senthil Kumar
doaj
The Role of Computer Graphics in Documentary Film Production [PDF]
We discuss a topic on the role of computer graphics in the production of documentaries, which is often ignored in favor of other topics. Typically, except for some rare occasions, documentary producers and computer scientists or digital artists that do computer graphics are relatively far apart in their domains and rarely intercommunicate to have a ...
arxiv
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source