Results 131 to 140 of about 666,291 (363)

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Image Laundering

open access: yesA Peer-Reviewed Journal About
This essay examines the layered structure of digital images in the context of the war in Ukraine, with a focus on how foregrounds and backgrounds are visually and conceptually manipulated to shape perception.
Katya Sivers
doaj   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

open access: yesFEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Medical station for image processing and visualization of the brain electrical activity on a three-dimensional reconstruction of the patient's head

open access: yesIngeniería e Investigación, 2003
This paper presents a review of some researchs in the computer graphics field conducted by OHWAHA to solve medical problems. Particulary, a frame work to generate a three-dimensional human head model from a stack of brain images obtained by magnetic ...
Manuel Guillermo Forero, Duvier Zulanga
doaj  

Efficacy of Navigation in Skull Base Surgery Using Composite Computer Graphics of Magnetic Resonance and Computed Tomography Images.

open access: gold, 2001
Nakamasa Hayashi   +6 more
openalex   +2 more sources

Most autophagic cell death studies lack evidence of causality

open access: yesFEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

PANINI PROJECTION EFFECT AS MEANS OF REDUCING PERSPECTIVE DISTORTIONS

open access: yesСистемный анализ и прикладная информатика, 2016
The method based on Panini projection to reduce perspective distortions of images with wide viewing angle is considered. The analysis of the features of construction of Panini projection is provided.
P. A. Kachanov   +2 more
doaj  

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