Results 71 to 80 of about 685,582 (289)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Computer-mediated group communication and ideation performance [PDF]

open access: yesInternational Journal of Business Science and Applied Management, 2012
Computer-based group idea generation is used in a variety of organizational settings to generate ideas that are helpful in attaining a goal. In such situations, the characteristics of the interaction may impact on the group processes, and accordingly on ...
Gressgård, L.J.
doaj  

L2 Engagements on Facebook: A Survey on the Network's Usefulness for Voluntary German and Japanese Learning

open access: yesThe EUROCALL Review, 2020
In this paper the results of an online survey (n=210) regarding the usefulness of Facebook for informal L2 learning will be presented. Participants were individual Facebook users who study either German (n=118) or Japanese (n=92).
Axel Harting
doaj   +1 more source

Affective interactions between expressive characters [PDF]

open access: yes, 2004
When people meet in virtual worlds they are represented by computer animated characters that lack a variety of expression and can seem stiff and robotic.
Ballin, D, Gillies, M
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Computer Mediated Communication and the Connection between Virtual Utopias and Actual Realities [PDF]

open access: yes, 1998
People have generally been very ambivalent about the potential future roles of new technologies (and the internet specifically) and their possible effects on human society.
Richards, Cameron
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Cross-Cultural Pragmatic Failure in Computer-Mediated Communication

open access: yesCoolabah, 2011
The study reported in this paper examines the occurrence of cross-cultural misunderstandings in computer-mediated communication (CMC). CMC has become a part of many people’s everyday life; rules of language practice such as politeness and other ...
Martina Baumer, Henriette van Rensburg
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Technology-Enhanced Learning for Graduate Students: Exploring the Correlation of Media Richness and Creativity of Computer-Mediated Communication and Face-to-Face Communication

open access: yesApplied Sciences, 2020
The objective of the research was to explore and compare the differences in potential creative thinking that media richness had on learners in creativity training through two different types of communication formats; computer-mediated communication, and ...
Shan-Hui Chao   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy