Results 51 to 60 of about 638,465 (316)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Disassortativity of computer networks [PDF]
2016 IEEE Conference on Intelligence and Security Informatics (ISI), 2016 Network data is ubiquitous in cyber-security applications. Accurately modelling such data allows discovery of anomalous edges, subgraphs or paths, and is key to many signature-free cyber-security analytics. We present a recurring property of graphs originating from cyber-security applications, often considered a ‘corner case’ in the main literature on ...
Patrick Rubin-Delanchy +2 more
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A bibliometric overview of the Journal of Network and Computer Applications between 1997 and 2019
, 2020 © 2020 Elsevier Ltd A bibliometric analysis of the Journal of Network and Computer Applications (JNCA) for the 1997–2019 period is performed. This analysis uncovers the structural and hidden implications of this journal.
Merigó, JM +5 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Review of KDD Cup ‘99, NSL-KDD and Kyoto 2006+ datasets / Обзор KDD Cup ‘99, NSL-KDD и Kyoto 2006+ баз данных / Pregled KDD Cup '99, NSL-KDD i Kyoto 2006+ baza podataka [PDF]
Vojnotehnički Glasnik, 2018 This paper presents a review of three datasets, namely KDD Cup ‘99, NSL-KDD and Kyoto 2006+ datasets, which are widely used in researching intrusion detection in computer networks.
Danijela D. Protić
doaj +1 more source
Privacy-enhanced social-network routing
, 2011 This work is supported by the UK Engineering and Physical Sciences Research Council and the Technology Strategy Board as part of the Privacy Value Networks project, EP/G002606/1.Opportunistic networking—forwarding messages in a disconnected mobile ad hoc
Parris, Iain Siraj +3 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
GBSS:researches on group-based semantic search
Tongxin xuebao, 2006 A group-based semantic search method-GBSS was presented.With regard to architecture,GBSS introduced a hybrid architecture in which the storage and search of raw data was based on DHT network,but the storage and search of meta-data was based on ...
CHEN Hai-tao +2 more
doaj