Results 211 to 220 of about 575,292 (267)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Development of a Digital Multimodal Pain Intervention (CHRONIC): Protocol for a Randomized Controlled Trial Study. [PDF]

JMIR Res Protoc
Bunjaku G, Fellbaum L, Laufhütte A, Zimmermann T.   +3 more
europepmc   +1 more source

Robot-assisted jaw-in-a-day based on the sandwich approach: case series. [PDF]

Maxillofac Plast Reconstr Surg
Luo P, Gao X, Su L, Chen H, Deng J, Ren X, Fu G, Huang Y, Ou Z, Zhang F.   +9 more
europepmc   +1 more source

Peering Inside the Black Box: Explainable AI to Interpret Advanced Computer Vision Fungal Pathogen Prediction. [PDF]

Sci Rep
Guthrie JD, Shankarnarayan SA, Charlebois DA.   +2 more
europepmc   +1 more source

Enhancing Therapist Training in the Delivery of Exposure Therapy for Individuals with Anxiety Disorders Using Virtual Reality Simulation: Randomized Feasibility Trial. [PDF]

JMIR Med Educ
Kemp J, Rosen A, Kim H, Adams Larsen M, Benito K, Freeman J, Machan J, Tuerk P.   +7 more
europepmc   +1 more source

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The Logic of Computer Programming

IEEE Transactions on Software Engineering, 1978
Techniques derived from mathematical logic promise to provide an alternative to the conventional methodology for constructing, debugging, and optimizing computer programs. Ultimately, these techniques are intended to lead to the automation of many of the facets of the programming process.
Zohar Manna, Richard J. Waldinger
openaire   +2 more sources

Biomolecular Computing and Programming

IEEE Transactions on Evolutionary Computation, 1999
Molecular computing is a discipline that aims at harnessing individual molecules at nanoscales to perform computations. The best studied molecules for this purpose to date have been DNA and bacteriorhodopsin. Biomolecular computing allows one to realistically entertain, for the first time in history, the possibility of exploiting the massive ...
Max H. Garzon, Russell J. Deaton
openaire   +1 more source