Results 211 to 220 of about 4,700,141 (242)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Community-based cancer navigation and support program: What are the activities and how much does it cost? [PDF]

Prev Oncol Epidemiol
Hoover S, Gerrish K, Poveda P, Krudy M, Subramanian S.   +4 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Digital Health Approaches to Geriatric Rehabilitation: A Narrative Paper. [PDF]

Ann Rehabil Med
Moon C, Bregasi P, Khandan A, Najafi B.
europepmc   +1 more source

Influence of conventional and AI-assisted dental CAD software and 3D printing technology on the intaglio surface trueness of interim crowns. [PDF]

J Adv Prosthodont
Kim J, Son K, Kim SY, Lee KB.
europepmc   +1 more source

From Innovation to Implementation: A Scoping Review of Simulation in Otolaryngology Education. [PDF]

Laryngoscope Investig Otolaryngol
Yim MT, Latour M, Vasudevan SS.
europepmc   +1 more source

Should Artificial Intelligence Literacy Be Integrated in Postgraduate Endodontic Programs? [PDF]

Int Dent J
Turky M.
europepmc   +1 more source

Harnessing high-throughput phenotyping and artificial intelligence for soybean breeding: From trait assessment to data-driven decisions. [PDF]

Plant Phenomics
Chagas JTB, Araújo MS, Pavan JPS, Françani AO, Ferreira GNC, Stella AA, Martinez M, Retore YI, Fregonezi BF, Martins GM, Zhao T, Zhou J, Sousa DR, Gao Y, Ji D, Gao K, Li B, Liu S, Zhao L, Pinheiro JB.   +19 more
europepmc   +1 more source

Artificial Intelligence-Assisted Colonoscopy for Colorectal Lesion Detection: Current Evidence, Challenges, and Future Directions. [PDF]

J Clin Med
Antzoulas A, Mulita F, Leivaditis V, Liolis E, Dimopoulos P, Tzelepi V, Maroulis I, Anagnostopoulos CN.   +7 more
europepmc   +1 more source