Results 91 to 100 of about 35,870,954 (296)
Advances in Computer Science and Engineering
, 2012 This book includes the proceedings of the second International Conference on Advances in Computer Science and Engineering (CES 2012), which was held during January 13-14, 2012 in Sanya, China.
Zeng, Dehuai
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Where's the science in software engineering?
Ubiquity, 2014 This article is a personal account of the methodological evolution of software engineering research from the 1970s to the present.
openaire +2 more sources
Innovations in Computing Sciences and Software Engineering [PDF]
, 2010 Innovations in Computing Sciences and Software Engineering includes a set of rigorously reviewed world-class manuscripts addressing and detailing state-of-the-art research projects in the areas of Computer Science, Software Engineering, Computer Engineering, and Systems Engineering and Sciences.
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Computer Science and Engineering Doctoral Degree Annual Program Outcomes Assessments, 2019-20 [PDF]
, 2020 This report reviews Wright State University\u27s Computer Science and Engineering Doctoral Degree program for the 2019-2020 academic ...
College of Engineering and Computer Science, Wright State University
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A New Approach to Teaching Mathematics in Universities
Открытое образование (Москва)The aim of this paper is to develop a methodology for teaching mathematics at universities that makes extensive use of modern digital and information technologies.
V F. Ochkov +2 more
doaj +1 more source
Complexity, 2019 Decomposition-based multiobjective evolutionary algorithms (MOEA/Ds) have become increasingly popular in recent years. In these MOEA/Ds, evolutionary search is guided by the used weight vectors in decomposition function to approximate the Pareto front ...
Wu Lin +5 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Computer Science and Engineering Doctoral Degree Academic Program Review, 2019
, 2020 This report reviews Wright State University\u27s Computer Science and Engineering Doctoral program, specifically looking at the time from Fall 2015 to Fall ...
College of Engineering and Computer Science, Wright State University
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