Results 131 to 140 of about 35,870,954 (296)

Complementary Local–Global Optimization for Few-Shot Object Detection in Remote Sensing

open access: yesRemote Sensing
Few-shot object detection (FSOD) in remote sensing remains challenging due to the scarcity of annotated samples and the complex background environments in aerial images.
Yutong Zhang   +7 more
doaj   +1 more source

Innovating at the Intersection: Software Engineering for Science and Industry

open access: yes
This paper provides a summary of the keynote talk ’Innovating at the Intersection: Software Engineering for Science and Industry’ held at the conference Software Engineering ...
Felderer, Michael
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The Influence of Software Engineering Education on Developing Teamwork Skills in Both Genders

open access: yesIEEE Access
Teamwork is recognized as a highly valuable skill for any software engineer. In computer science programs it is typically developed through project-based courses, though these courses often do not adopt a gender-oriented approach.
Maria Cecilia Bastarrica   +1 more
doaj   +1 more source

An engineering discipline of software: an Australian perspective [PDF]

open access: yes, 1997
Engineering faculties within Australian universities are being asked to explore the feasibility of mounting separate Software Engineering programmes.
Armarego, J., Cohen, R.F.
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

CytoAnalyst web platform facilitates comprehensive single cell RNA sequencing analysis

open access: yesScientific Reports
Single-cell technologies have revolutionized our ability to study cellular heterogeneity and dynamics at unprecedented resolutions. In this fast-growing field, it becomes increasingly challenging to navigate the vast number of tools and steps for ...
Phi Bya   +4 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

WTP : electrical engineering and computer science outreach for high school students

open access: yes, 2002
Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2002.Includes bibliographical references (leaves 47-48).This electronic version was submitted by the student author.
Ricket, Douglas J. (Douglas James), 1979-
core  

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