Results 61 to 70 of about 35,870,954 (296)
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Computer Science and Engineering Doctoral Degree Annual Program Outcomes Assessments, 2022-23 [PDF]
, 2023 This report reviews Wright State University\u27s Computer Science and Engineering Doctoral Degree program for the 2022-2023 academic ...
College of Engineering and Computer Science, Wright State University
core +1 more source
Offline and online energy-efficient monitoring of scattered uncertain logs using a bounding model [PDF]
Logical Methods in Computer ScienceMonitoring the correctness of distributed cyber-physical systems is essential. Detecting possible safety violations can be hard when some samples are uncertain or missing. We monitor here black-box cyber-physical system, with logs being uncertain both in
Bineet Ghosh, Étienne André
doaj +1 more source
Simulink bus usage in practice: an empirical study
, 2023 Institute of Computer ScienceInstitute of Computer Science, Software Engineering Group (SEG ...
Boll, Alexander +5 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Education SciencesAI Assess, a ChatGPT-based assessment system utilizing the ChatGPT platform by OpenAI, composed of four components, is proposed herein. The components are tested on the GPT model to determine to what extent they can grade various exam questions based on ...
Ayman Diyab +3 more
doaj +1 more source
Revista Facultad de Ingeniería Universidad de Antioquia, 2015 Just a little bit more than three decades has passed since IBM introduced the personal computer (PC), and this technology started to be introduced easier into the daily life of different kind of companies.
Julian David Arias-Londoño +1 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Large-scale complex IT systems [PDF]
, 2012 12 pages, 2 figuresThis paper explores the issues around the construction of large-scale complex systems which are built as 'systems of systems' and suggests that there are fundamental reasons, derived from the inherent complexity in these systems, why ...
Cliff, Dave +7 more
core +1 more source