Results 231 to 240 of about 34,541,972 (297)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

AbAgKer: a unified semi-supervised framework for antigen-antibody binding affinity and kinetics prediction. [PDF]

Bioinformatics
Luo G, Wang J, Zhang S, Zhu Z, Lu Z, Li M.   +5 more
europepmc   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

grafify online: A web app for graphing and statistical analysis. [PDF]

PLoS Biol
Shenoy AR.
europepmc   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Systems biology during 20 years of PLoS Computational Biology. [PDF]

PLoS Comput Biol
Alber M, Birtwistle MR, Finley SD, Mendes P.   +3 more
europepmc   +1 more source

SRLST: a unified multimodal representation learning framework for spatial transcriptomics analysis. [PDF]

Bioinformatics
Lan W, Deng X, Ling T, He G, Yan X, Zheng R, Li M, Pan S, Pan Y.   +8 more
europepmc   +1 more source

SIMLINK enables accurate variant pathogenicity prediction through modeling the gene-variant-feature association structure. [PDF]

Bioinformatics
Li HD, Wang C, Yan D, Huang W, Li Z, Wang S.   +5 more
europepmc   +1 more source

LAFA: a framework for reproducible longitudinal assessment of protein function annotation models. [PDF]

Bioinform Adv
Phan A, Wang Y, Boadu F, Cheng J, Radivojac P, Friedberg I.   +5 more
europepmc   +1 more source

Research on automatic segmentation method of microseismic monitoring signal under low signal-to-noise ratio conditions. [PDF]

PLoS One
Liu W, Li J, Zhang Z, Yuan Z, Teng S, Song D, Zhu M, Lv W.   +7 more
europepmc   +1 more source