Results 41 to 50 of about 34,540,832 (298)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

International Seminar on Software Engineering Computer Systems 2011 [PDF]

, 2011
Faculty of Computer Systems & Soft ware Engineering (FSKKP) Universiti Malaysia Pahang (UMP) in collaboration with the Information Society Digital and Wireless Communications (SDIWC) had organized the International Seminar on Software Engineering ...
UMP, .
core   +2 more sources

Barriers Faced by Women in Software Development Projects

Information, 2019
Computer science is a predominantly male field of study. Women face barriers while trying to insert themselves in the study of computer science. Those barriers extend to when women are exposed to the professional area of computer science. Despite decades
Edna Dias Canedo, Heloise Acco Tives, Madianita Bogo Marioti, Fabiano Fagundes, José Antonio Siqueira de Cerqueira   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

QuickVol: A lightweight browser tool for immersive visualizations of volumetric data

iScience
Summary: Volumetric layouts of data are becoming increasingly common in a number of fields. Visualizing these data often requires downloading a large suite of dedicated tools with a significant learning curve.
Maxim Kuznetsov, Mircea Teodorescu, Mohammed A. Mostajo-Radji, Sri Kurniawan   +3 more
doaj   +1 more source

A pragmatic workflow for research software engineering in computational science

CoRR, 2023
arXiv admin note: text overlap with arXiv:2208 ...
Tomislav Maric, Dennis Gläser, Jan-Patrick Lehr, Ioannis Papagiannidis, Benjamin Lambie, Christian H. Bischof, Dieter Bothe   +6 more
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Research and application of clustering algorithm for arbitrary data set [PDF]

, 2008
Paper presented at the 2008 International Conference on Computer Science and Software Engineering, December 12-14, 2008, Wuhan, ChinaThis paper discusses the theory and algorithmic design of the CADD (clustering algorithm based on object density and ...
Song, Yu-Chen, M.J. O'Grady, O'Hare, G. M. P. (Greg M. P.), O'Grady, Michael J., G.M.P. O'Hare, O\u27Grady, Michael J., O\u27Hare, G. M. P. (Greg M. P.), Yu-Chen Song   +7 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Editorial:  Applied Computing 2023

مجلة بغداد للعلوم
Applied computing utilizes aspects of computer science to solve problems in several disciplines, including business, politics, education, and the environment.
Yousra Abdul Alsahib S. Aldeen, Yusliza Yusoff, Samira Naji Kadhim   +2 more
doaj   +1 more source