Results 71 to 80 of about 35,870,954 (296)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Software Engineering and eLearning: The MuSofT Project - www.musoft.org
E-learning and Education, 2005 eLearning supports the education in certain disciplines. Here, we report about novel eLearning concepts, techniques, and tools to support education in Software Engineering, a subdiscipline of computer science. We call this "Software Engineering eLearning"
Ernst-Erich Doberkat +5 more
doaj
Improved softmax loss for deep learning-based face and expression recognition
Cognitive Computation and Systems, 2019 In recent years, deep convolutional neural networks (CNN) have been widely used in computer vision and significantly improved the performance of image recognition tasks.
Jiancan Zhou +4 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Complexity, 2020 In recent years, a number of recombination operators have been proposed for multiobjective evolutionary algorithms (MOEAs). One kind of recombination operators is designed based on the Gaussian process model. However, this approach only uses one standard
Xunfeng Wu +5 more
doaj +1 more source
Personal Reflections on 50 Years of Scientific Computing: 1967–2017
, 2017 Computer hardware, software, numerical algorithms, and science and engineering applications are traced for a half century from the author's ...
Watson, Layne T.
core
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Computer Science and Engineering Doctoral Degree Annual Program Outcomes Assessments, 2020-21 [PDF]
, 2021 This report reviews Wright State University\u27s Computer Science and Engineering Doctoral Degree program for the 2020-2021 academic ...
College of Engineering and Computer Science, Wright State University
core +1 more source
Introductory educational laboratory experience for computer engineering undergraduates [PDF]
, 2001 Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2001.Includes bibliographical references (leaf 68).by Michael L.
Jacknis, Michael L., 1975-
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DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source