Results 81 to 90 of about 1,948,017 (269)

A Parameterisation of Algorithms for Distributed Constraint Optimisation via Potential Games

open access: yes, 2008
This paper introduces a parameterisation of learning algorithms for distributed constraint optimisation problems (DCOPs). This parameterisation encompasses many algorithms developed in both the computer science and game theory literatures. It is built on
Chapman, Archie   +2 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Modern Transformations of Economics: Neuroeconomics

open access: yesTheory, Methodology, Practice, 2016
Traditionally, economists have not been interested in the neural underpinnings of human behavior. According to the classical decision-making theory, a decision-maker is a perfectly rational cognitive agent ignoring the influence of emotions.
Tatevik Mkrtchyan
doaj   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Unix selon l’ordre des raisons : la philosophie de la pratique informatique

open access: yesPhilosophia Scientiæ, 2013
In philosophy of science, it is sometimes fruitful to examine whether technical concepts originate from a structural necessity, rather than from the contingency of invention.
Baptiste Mélès
doaj   +1 more source

Second Language Acquisition Theory Based Bilingual Teaching Methods of Computer Science [PDF]

open access: yesProceedings of 4th International Conference on Education, Language, Art and Intercultural Communication (ICELAIC 2017), 2017
Jingwen Chen, Fumin Ma
openaire   +1 more source

Relative directed homotopy theory of partially ordered spaces [PDF]

open access: yes, 2006
Algebraic topological methods have been used successfully in concurrency theory, the domain of theoretical computer science that deals with distributed computing. L. Fajstrup, E. Goubault, and M. Raussen have introduced partially ordered spaces (pospaces)
Kahl, Thomas
core   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Transfer Learning for Facial Emotion Recognition on Small Datasets [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics
In the context of human interactions, complexity science (CS) provides a way to understand the dynamics that arise from the interplay of different individuals.
Paolo Barile   +2 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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