Results 191 to 200 of about 30,070,977 (302)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Transforming scholarly landscapes: The influence of large language models on academic fields beyond computer science. [PDF]

PLoS One
Pramanick A, Hou Y, Mohammad SM, Gurevych I.   +3 more
europepmc   +1 more source

Introduction to the Special Issue on Computer Science Education. [PDF]

TechTrends, 2022
Connolly C, Hall T.
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Creativity across domains: Thoughts in Science, Engineering, Mathematics, Computer Science, Technology, and Art. [PDF]

PNAS Nexus
Ottino JM.
europepmc   +1 more source

Correction: Advances in artificial intelligence and computer science for computer-aided diagnosis of colorectal polyps: current status. [PDF]

Endosc Int Open, 2023
van Bokhorst QN, Houwen BB, Hazewinkel Y, Fockens P, Dekker E.   +4 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

CS-KG 2.0: A Large-scale Knowledge Graph of Computer Science. [PDF]

Sci Data
Dessí D, Osborne F, Buscaldi D, Reforgiato Recupero D, Motta E.   +4 more
europepmc   +1 more source

Ancestral Computing for Sustainability: Centering Indigenous Epistemologies in Researching Computer Science Education. [PDF]

TechTrends, 2023
López-Quiñones A, Martinez-Lopez M, Moreno Sandoval CD, Carroll-Miranda J, Lindala AE, Chatman MC, Fleming J, Shockley ET, Cadeau D, Flores-Reyes E.   +9 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source