Results 21 to 30 of about 30,508,134 (258)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Trustworthy artificial intelligence in healthcare
, 2023 In addition to several chances to enhance people's lives and the development of communities, economies, and healthcare, artificial intelligence (AI) similarly presents a number of brand-new social, legal, ethical, and technological issues. Since trust is
Subasi, Abdulhamit +4 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Breast tumor detection in ultrasound images using artificial intelligence
, 2023 Leveraging artificial intelligence (AI) for categorizing breast tumors as malignant or benign from breast ultrasound images can provide an effective and relatively low-cost method for the diagnosis of breast cancer.
Subasi, Abdulhamit, Modi, Omkar
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Breast cancer detection from mammograms using artificial intelligence
, 2023 Breast cancer is one of the fastest-growing forms of cancer in the world today. Breast cancer is primarily found in women, and its frequency has been gaining significantly in the last few years.
Subasi, Abdulhamit +3 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Learning models of sequential decision-making with partial specification of agent behavior
, 2019 Artificial agents that interact with other (human or artificial) agents require models in order to reason about those other agents’ behavior. In addition to the predictive utility of these models, maintaining a model that is aligned with an agent’s true ...
Shah, Julie A. +3 more
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Intelligent library systems: artificial intelligence technology and library automation systems [PDF]
, 1991 Artificial Intelligence (AI) encompasses the following general areas of research: (1) automatic programming, (2) computer vision, (3) expert systems, (4) intelligent computer-assisted instruction, (5) natural language processing, (6) planning and ...
Bailey, Jr., Charles W.
core +1 more source