Results 161 to 170 of about 29,700 (267)

Leveraging protein language models for cross-variant CRISPR/Cas9 sgRNA activity prediction. [PDF]

Bioinformatics
Hou Y, Li Y, Zheng R, Zhang F, Guo F, Li M, Zeng M.   +6 more
europepmc   +1 more source

Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins

Advanced Healthcare Materials, EarlyView.
Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer, Amelia Hasenauer, Dominic Rütsche, Hao Liu, Jakub Janiak, Michael Nguyen, Karen L. Christman, Marcy Zenobi‐Wong, Parth Chansoria   +8 more
wiley   +1 more source

Realfreq: real-time base modification analysis for nanopore sequencing. [PDF]

Bioinformatics
Samarasinghe S, Deveson I, Gamaarachchi H.   +2 more
europepmc   +1 more source

Structural Motifs in Soft Fibrous Tissues: Revealing Structure‐Mechanics Relationships in Deformation and Tear Resistance for Biomimetic Material Design

Advanced Healthcare Materials, EarlyView.
This review explores how soft fibrous tissues achieve their remarkable mechanical behavior through recurring structural motifs across multiple length scales. It highlights key advances in mimicking these features using fiber‐reinforced hydrogels and hierarchical composites, offering insights into mechanical compatibility, flaw tolerance, and tear ...
Mirit Sharabi
wiley   +1 more source

Graph representation learning via enhanced GNNs and transformers. [PDF]

Sci Rep
Mu H, Zhou C, Yu Q, Mu Q.
europepmc   +1 more source

Impact of Fiber Orientation in Electrospun PLA Scaffolds on Fluid Dynamics in a Custom Microfluidic Device

Advanced Healthcare Materials, EarlyView.
Fiber orientation in electrospun scaffolds affects permeability and fluid dynamics in microfluidic devices. Combining experimental data with computational fluid dynamic simulations, we show that aligned fibers enhance flow uniformity, reduce pressure and shear stress variability.
Elisa Capuana, Maria Testa, Chiara Di Marco, Francesco Lopresti, Vincenzo La Carrubba   +4 more
wiley   +1 more source

The Integration and Growth of R in Soil Research: A 10-Year Analysis. [PDF]

Ecol Evol
Gao M, Yan X, Li X, Zheng Y, Lai J.
europepmc   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Enabling data-driven discoveries in evolutionary genetics and genomics. [PDF]

Genetics
Kumar S.
europepmc   +1 more source

Human Skin Models in Biophotonics: Materials, Methods, and Applications

Advanced Healthcare Materials, EarlyView.
This review discusses how the optical properties of human skin can be replicated in human skin models. It describes the principles, materials, and techniques used to develop artificial skin for biophotonics research. Finally, the article highlights recent advances and shows how these models improve the study of light‐skin interactions without the need ...
Dardan Bajrami, Fabrizio Spano, Kongchang Wei, Mathias Bonmarin, René M. Rossi   +4 more
wiley   +1 more source