Results 51 to 60 of about 2,631,463 (266)

Enhancing the Verification-Driven Learning Model for Data Structures with Visualization [PDF]

open access: yes, 2011
The thesis aims at teaching various data structures algorithms using the Visualization Learning tool. The main objective of the work is to provide a learning opportunity for novice computer science students to gain a broader exposure towards data ...
Kondeti, Yashwanth Reddy
core   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

open access: yesFEBS Letters, EarlyView.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin   +2 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Crystal structure prediction using neural network potential and age-fitness Pareto genetic algorithm [PDF]

open access: yesarXiv, 2023
While crystal structure prediction (CSP) remains a longstanding challenge, we introduce ParetoCSP, a novel algorithm for CSP, which combines a multi-objective genetic algorithm (MOGA) with a neural network inter-atomic potential (IAP) model to find energetically optimal crystal structures given chemical compositions.
arxiv  

A Static Analysis Framework for Livelock Freedom in CSP [PDF]

open access: yesLogical Methods in Computer Science, Volume 9, Issue 3 (September 23, 2013) lmcs:884, 2013
In a process algebra with hiding and recursion it is possible to create processes which compute internally without ever communicating with their environment. Such processes are said to diverge or livelock. In this paper we show how it is possible to conservatively classify processes as livelock-free through a static analysis of their syntax.
arxiv   +1 more source

Application of Blended Learning in Data Structures and Algorithms Course Teaching

open access: yes, 2013
Data structures and algorithms course is a core foundation stone in a computer science curriculum. But there are many complicated algorithms in it. In order to help students to master the algorithms, this paper describes the use of blended learning in ...
Xiaojing Liu, Xiaoying Wang, Rui Wang
semanticscholar   +1 more source

Design patterns for the data structures and algorithms course

open access: yesTechnical Symposium on Computer Science Education, 1999
Design patterns have recently emerged as a vehicle for describing and documenting recurring object-oriented designs. More significantly, they offer up a long-awaited framework for teaching good software design.
B. R. Preiss
semanticscholar   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Evaluating Online Tutorials for Data Structures and Algorithms Courses

open access: yes, 2013
We present results from a study investigating the role of online tutorials for data structures and algorithms (DSA) courses in Computer Science. We used principles drawn from research and theories in disciplines such as cognitive science, motivation, and
S. Hall   +4 more
semanticscholar   +1 more source

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