Results 61 to 70 of about 2,631,463 (266)
Molecular Oncology, EarlyView.This study shows that patients with gastrointestinal adenocarcinomas can be stratified into six distinct subtypes based on genome‐scale DNA methylation profiling. This stratification, achieved using a robust analytical framework, aligns with established tumor characteristics and holds potential to support prognostication.
Rita Pinto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Ultra-large-scale electronic structure theory and numerical algorithm [PDF]
arXiv, 2008 This article is composed of two parts; In the first part (Sec. 1), the ultra-large-scale electronic structure theory is reviewed for (i) its fundamental numerical algorithm and (ii) its role in nano-material science. The second part (Sec. 2) is devoted to the mathematical foundation of the large-scale electronic structure theory and their numerical ...
arxiv
Structure-Preserving Geometric Particle-in-Cell Methods for Vlasov-Maxwell Systems [PDF]
, 2018 Recent development of structure-preserving geometric particle-in-cell (PIC) algorithms for Vlasov-Maxwell systems is summarized. With the arriving of 100 petaflop and exaflop computing power, it is now possible to carry out direct simulations of multi-scale plasma dynamics based on first-principles. However, standard algorithms currently adopted by the
arxiv +1 more source
Electrical circuit simulation [PDF]
, 2020 Treballs Finals de Grau de Matemàtiques, Facultat de Matemàtiques, Universitat de Barcelona, Any: 2020, Director: Antoni Benseny[en] Given an electrical circuit, formed by wires, nodes, batteries and resistors, the main goal of this work is to solve this
Arago Delage, Julie Isabel
core
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Algorithm for Predicting Protein Secondary Structure [PDF]
Journal of Computer Science and Engineering, Volume 1, Issue 1,
p68-71, May 2010, 2010 Predicting protein structure from amino acid sequence is one of the most important unsolved problems of molecular biology and biophysics.Not only would a successful prediction algorithm be a tremendous advance in the understanding of the biochemical mechanisms of proteins, but, since such an algorithm could conceivably be used to design proteins to ...
arxiv
How should data structures and algorithms be taught
Annual Conference on Innovation and Technology in Computer Science Education, 1999 Data Structures and Algorithms is clearly a very important topic and course in the Computer Science curriculum. It has been taught at several levels by a number of approaches. Should the approach be mathematical, theoretical and abstract or very concrete
Danny Kopec, Richard T. Close, Jim Aman
semanticscholar +1 more source
Enhanced detection in CT colonography using adaptive diffusion filtering [PDF]
, 2009 Computer-aided detection (CAD) is a computerized procedure in medical science that supports the medical team’s interpretations and decisions. CAD uses information from a medical imaging modality such as Computed Tomography to detect suspicious lesions ...
Beddoe, G. +5 more
core +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source