Results 121 to 130 of about 287,793 (266)

Multi-plane vision transformer for hemorrhage classification using axial and sagittal MRI data. [PDF]

Sci Rep
Das BK, Zhao G, Mailhe B, Re TJ, Comaniciu D, Gibson E, Maier A.   +6 more
europepmc   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

A Bayesian Framework with Dirichlet Priors and Spatial Smoothing for Protein Rotamer Prediction. [PDF]

Int J Mol Sci
Al Nasr K, Jad Allah A, Alamri M, Al Sallal M.   +3 more
europepmc   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

ROS 4 healthcare: a framework for physiological human sensing for social, assistive, rehabilitation, and medical robotics. [PDF]

Front Robot AI
Manríquez-Cisterna RJ, Mishra P, Peña-Queralta J, Perez-Serrano M, Garyfallidis S, Kupper L, Ejtehadi M, Breuss A, Ravankar AA, Salazar Luces JV, Riener R, Hirata Y, Paez-Granados D.   +12 more
europepmc   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Hybrid Deep Learning Framework for Sleep Quality Prediction: Integrating Metaheuristic Optimization and Statistical Features. [PDF]

Brain Behav
Lasisi A, Rathore N, Gupta L, Thakur K, Burje S, Ramasamy M, Bhad S, Sinha A, Jeet A, Singh S, Naveed QN, Kumar R, Hussain SA.   +12 more
europepmc   +1 more source

A New Zealand digital library for computer science research

, 1995
Ian H. Witten, Sally Jo Cunningham, Mahendra Vallabh, Tim Bell   +3 more
openalex   +1 more source

Interacting with information resources: designing libraries for learning [PDF]

, 2006
Blandford, A
core  

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source