Results 191 to 200 of about 348,900 (301)

Digital Health Tool for Preventing Blindness From Diabetic Retinopathy: Protocol for a Qualitative Study.

JMIR Res Protoc
Frimpong A, Granados A, Chang T, Fu J, Applebaum SS, Moore SG, Kaur M, Adepoju B, Hari Krishnan V, Levi A, McCall T, Nwanyanwu KH.   +11 more
europepmc   +1 more source

Advancing large-molecule discovery with a unified digital platform for data analysis and workflow management. [PDF]

MAbs
Natali E, Hersch J, Freiberg C, Steigele S.   +3 more
europepmc   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Accelerating compound synthesis in drug discovery: the role of digitalisation and automation. [PDF]

RSC Med Chem
Nippa DF, Boddy AJ, Atz K, Grether U, Binch H, Martin RE.   +5 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Taiwan's Smart Healthcare Value Chain: AI Innovation from R&D to Industry Deployment. [PDF]

Healthcare (Basel)
Lin TM, Yang HW, Han CC, Lin CS.
europepmc   +1 more source

Ratoon Season Rice Reduces Methane Emissions by Limiting Acetic Acid Transport to the Rhizosphere and Inhibiting Methanogens

Advanced Science, EarlyView.
This study finds that the interaction between ABA‐OsCIPK2‐OsSWEET1A reduces the allocation of methane producing bacteria carbon source (acetic acid) content to the rhizosphere soil of ratoon season rice, thereby reducing methane emissions. Abstract Rice paddies are a major, persistent source of atmospheric methane (CH4), emission rates depend on the ...
Jingnan Zou, Hailong Xu, Bin Qin, Chaojie Lan, Jinying Li, Bianhong Zhang, Huabin Zhang, Chunlin Guo, Hongfei Chen, Zhongming Fang, Quanzhi Zhao, Wenfei Wang, Changxun Fang, Zhixing Zhang, Wenxiong Lin   +14 more
wiley   +1 more source

Incident-aware smart prioritization framework for penetration testing and prevention of URL-based cybersecurity attacks in industry 4.0 IoT networks. [PDF]

Sci Rep
Nurlan Z, Gabdullayev D, Mukhametzhanova B, Zhakiyev N, Sonny I, Ala'anzy MA, Ahmad Z, Amirgaliyev B.   +7 more
europepmc   +1 more source

Edible and Recyclable Gelatin‐Based Electronics for High‐Precision Health and Environmental Monitoring

Advanced Science, EarlyView.
An edible and recyclable composite film composed of gelatin and activated charcoal is presented for multifunctional health and environmental monitoring. The edible films exhibit tuneable mechanical and electrical properties, along with multimodal sensing capabilities for strain, humidity, and temperature. The composite film is degradable and recyclable,
Ming Dong, Pietro Cataldi, Han Zhang, Emiliano Bilotti, Conor Boland, Athanassia Athanassiou, Dimitrios G. Papageorgiou   +6 more
wiley   +1 more source

An Inclusive Offline Learning Platform Integrating Gesture Recognition and Local AI Models. [PDF]

Biomimetics (Basel)
Drăgoi MV, Nisipeanu I, Puiu RA, Tache FG, Spiridon-Mocioacă TM, Hank A, Cristoiu C.   +6 more
europepmc   +1 more source