Results 21 to 30 of about 285,794 (238)
The intention to use mobile digital library technology: A focus group study in the United Arab Emirates [PDF]
, 2015 IGI Global (“IGI”) granted Brunel University London the permission to archive this article in BURA (http://bura.brunel.ac.uk).This paper presents a qualitative study on student adoption of mobile library technology in a developing world context.
E. M.Rogers +13 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Smart Topic Miner: Supporting Springer Nature Editors with Semantic Web Technologies [PDF]
, 2016 Academic publishers, such as Springer Nature, annotate scholarly products with the appropriate research topics and keywords to facilitate the marketing process and to support (digital) libraries and academic search engines.
Birukou, Aliaksandr +3 more
core
Evaluation of Use of Consortium of e-Resources in Agriculture in Context of Kerala Agricultural University [PDF]
, 2012 As digital information resources available online are increasing at an exponential rate, several practices have evolved for the economic and effective delivery of such information to the end users.
Francis, A.T.
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Digital Preservation Education in iSchools [PDF]
, 2010 This poster investigates digital preservation education in the iSchool caucus. The project identifies core concepts addressed in digital preservation coursework in iSchools and identifies possible areas for curriculum development.
Costello, Kaitlin
core
Judging a book by its cover: interface elements that affect reader selection of ebooks [PDF]
, 2012 Digital library research has demonstrated the impact of content presentation on both search and reading behaviours. In this paper, we scrutinise the influence of ebook presentation on user behaviour, focussing on document thumbnails and the first page ...
Buchanan, George +5 more
core +3 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source