Results 21 to 30 of about 21,436 (248)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Digital Library Education in Computer Science Programs [PDF]

, 2014
In an effort to identify the “state of the art” in digital library education in computer science (CS) programs, we analyzed CS courses on digital libraries and digital library-related topics. Fifteen courses that mention digital libraries in the title or
Fox, Edward A., Wildemuth, Barbara M., Pomerantz, Jeffrey P., Yang, Seungwon, Oh, Sanghee   +4 more
core  

Assembling and enriching digital library collections [PDF]

, 2003
People who create digital libraries need to gather together the raw material, add metadata as necessary, and design and build new collections. This paper sets out the requirements for these tasks and describes a new tool that supports them interactively,
Thompson, John, Bainbridge, David, Witten, Ian H.   +2 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Digital libraries on an iPod: Beyond the client-server model [PDF]

, 2007
This paper describes an experimental system that enhanced an iPod with digital library capabilities. Using the open source digital library software Greenstone as a base, this paper more specifically maps out the technical steps necessary to achieve this,
Jones, Matt, Bainbridge, David, Jones, Steve, McIntosh, Samuel John   +3 more
core  

That's 'é' not 'þ' '?' or '☐': a user-driven context-aware approach to erroneous metadata in digital libraries [PDF]

, 2011
In this paper we present a novel system for user-driven integration of name variants when interacting with web-based information systems. The growth and diversity of online information means that many users experience disambiguation and collocation ...
Nichols, David M., Bainbridge, David, David M. Nichols, David Bainbridge, Twidale, Michael B., Michael B. Twidale   +5 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Constructing digital library interfaces [PDF]

, 2007
The software technologies used to create web interfaces for digital libraries are discussed using examples from Greenstone ...
Nichols, David M., Bainbridge, David, David M. Nichols, David Bainbridge, Twidale, Michael B., Michael B. Twidale   +5 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Scalable Storage for Digital Libraries [PDF]

, 2002
I propose a storage system optimised for digital libraries. Its key features are its heterogeneous scalability; its integration and exploitation of rich semantic metadata associated with digital objects; its use of a name space; and its aggressive ...
Mather, Paul
core