MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis
This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang +18 more
wiley +1 more source
Editorial: Interdisciplinary synergies in neuroinformatics, cognitive computing, and computational neuroscience. [PDF]
Deb N, Khan Z, Sulaiman M, Abu Bakar M.
europepmc +1 more source
Highly Efficient Discovery of 3D Mechanical Metamaterials via Monte Carlo Tree Search
Machine learning (ML), as a data‐driven method, has revolutionized metamaterial design, surpassing traditional intuition‐driven trial‐and‐error methods in both efficiency and performance. Here, MCTS‐AL, an active learning framework integrating finite element simulation (FEM), convolutional neural networks (CNNs), and Monte Carlo Tree Search (MCTS ...
Jiamu Liu +4 more
wiley +1 more source
Single-phase full-bridge inverter control based on discrete adaptive sliding mode algorithm with error compensation. [PDF]
Zhang Y, Tang Z, Xu F, Zhou K, Yang K.
europepmc +1 more source
Surface Adhesion Engineering for Armored Metasurfaces and Beyond
Targeting primary causes of dysfunctionality in optical systems, an “armored” metasurface is developed based on Persson's model and Hertzian theory, enabling anti‐dust, anti‐scratch, anti‐impact, and anti‐water, heat resistance capabilities, alongside excellent optical antireflection performance.
Lianwei Chen +10 more
wiley +1 more source
New bounds of the smoothing parameter for lattices. [PDF]
Guo H, Liu F, Wang L, Tian K.
europepmc +1 more source
A General and Efficient Framework for the Rapid Design of Miniaturized, Wideband, and High‐Bit RIS
A general and efficient framework is proposed for the rapid design of high‐performance reconfigurable intelligent surfaces (RISs). This framework integrates advanced antenna design techniques and incorporates various load types, quantities, and values to achieve the design of high‐performance RISs.
Jun Wei Zhang +14 more
wiley +1 more source
Edge percolation centrality: A new measure to quantify the influence of edges during percolation in networks. [PDF]
Durón C, Kravitz H, Brio M.
europepmc +1 more source
High‐voltage cycling of layered alkali transition metal oxides in Li‐ and Na‐ion cells increases energy density but diminishes lifetime. A novel XRD‐analysis method, centered on the stacking factor “z”, is developed to quantify the stacking fractions in the OP hybrid structure.
Libin Zhang +3 more
wiley +1 more source
Mathematical insights into epidemic spread: A computational and numerical perspective. [PDF]
Alsulami A +5 more
europepmc +1 more source

