Results 101 to 110 of about 46,626,028 (241)

Fundamental limits incorporating logical reasoning into Shannon's information theory. [PDF]

Proc Natl Acad Sci U S A
Lastras LA, Lenchner J, Trager BM, Szpankowski W, Squillante MS, Wu CW, Fagin R, Gray A.   +7 more
europepmc   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Corrigendum to "Convergence of computer-aided drug discovery and artificial intelligence: Towards next-generation therapeutics" [Pharm. Sci. Adv. 4 (2026) 100100]. [PDF]

Pharm Sci Adv
Zheng L, Cao J, Jing L, Kang D, Wang Z, Liu X.   +5 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Can LLMs improve the accuracy of behavior prediction for personnel in high-stakes scenarios by predicting emotions? - A fine-tuning study based on scarce homogeneous cultural data in high-pressure environments. [PDF]

PLoS One
Chen Y, Ping Y, Zhou S, Jojo C.
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Trust formation and fairness perception in GenAI: the divergent psychological pathways of computer science and business-related students. [PDF]

BMC Psychol
Jia C, Li H, Wu L, Xu Z, Shen L, Liu Y, Wang D.   +6 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

F-squares over cellular automata. [PDF]

PLoS One
Hall J, Morgan K, Stylianou S, Warnakulasooriyage V.   +3 more
europepmc   +1 more source