Results 171 to 180 of about 2,128,813 (227)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Development and Formative Usability Evaluation of a Theory-Driven Progressive Web Application for Young Adult Wellness Engagement (MiCARE): Protocol for a Mixed Methods Study.

JMIR Res Protoc
Thanthrige A, Wickramasinghe N.
europepmc   +1 more source

Population structure reverses selection of variants with proportionally scaled birth and death rates. [PDF]

Nat Commun
Komarova NL, Wodarz D.
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

AI-driven transformation in forensic medicine education: applications, pedagogical shifts, and future challenges. [PDF]

Front Med (Lausanne)
Wu YQ, Du Y.
europepmc   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

How public involvement can improve the science of AI. [PDF]

Proc Natl Acad Sci U S A
Matias JN, Price M.
europepmc   +1 more source

Enhanced Dual-Axis Rotation Modulation Scheme for Inertial Navigation Systems Using a 64-Position Approach. [PDF]

Sensors (Basel)
Chen H, Wang Z, Sun H, Gu D, Miao C, Ye W.   +5 more
europepmc   +1 more source

The future of fundamental science led by generative closed-loop artificial intelligence. [PDF]

Front Artif Intell
Zenil H, Tegnér J, Abrahão FS, Lavin A, Kumar V, Frey JG, Weller A, Soldatova L, Bundy AR, Jennings NR, Takahashi K, Hunter L, Dzeroski S, Briggs A, Gregory FD, Gomes CP, Rowe J, Evans J, Kitano H, King R.   +19 more
europepmc   +1 more source

A quantitative measurement of dichoptic color difference thresholds related to binocular luster across various luminance. [PDF]

Iperception
Su J, Guan H, Chen Z.
europepmc   +1 more source