Results 31 to 40 of about 2,138,936 (230)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Who Cares about Axiomatization? Representation, Invariance, and Formal Ontologies [PDF]
, 2006 The philosophy of science of Patrick Suppes is centered on two important notions that are part of the title of his recent book (Suppes 2002): Representation and Invariance.
Ferrario, R.
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, 2018 Quantum computers are a promising candidate to radically expand computational science through increased computing power and more effective algorithms. In particular quantum computing could have a tremendous impact in the field of quantum cosmology.
Kocher, Charles D., McGuigan, Michael
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Проблеми державної інформаційної політики: гармонізація міжнародного і національного інформаційного права [PDF]
, 2002 Розглядаються питання формування державної інформаційної політики України, теорії інформаційного права, правової інформатики у контексті національної та міжнародної інформаційної безпеки.The questions of creation of state information policy of Ukraine ...
Гавловський, Владислав +3 more
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Інформаційна безпека, як нова парадигма нового кримінального кодексу України [PDF]
, 2001 Розглядаються питання теорії кримінального та інформаційного права, правової інформатики щодо інформаційної безпеки та захисту інформації в автоматизованих системах.In the article the questions of the theory of the crime and the information right, legal ...
Гавловський, Владислав +1 more
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