Results 21 to 30 of about 774,920 (290)

Tarski's influence on computer science

open access: yes, 2006
The influence of Alfred Tarski on computer science was indirect but significant in a number of directions and was in certain respects fundamental. Here surveyed is the work of Tarski on the decision procedure for algebra and geometry, the method of ...
Prakash Panangaden, Solomon Feferman
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Completeness of Flat Coalgebraic Fixpoint Logics

open access: yes, 2010
Modal fixpoint logics traditionally play a central role in computer science, in particular in artificial intelligence and concurrency. The mu-calculus and its relatives are among the most expressive logics of this type.
Gastin, P.   +3 more
core   +1 more source

Proof equivalence in MLL is PSPACE-complete [PDF]

open access: yes, 2016
MLL proof equivalence is the problem of deciding whether two proofs in multiplicative linear logic are related by a series of inference permutations. It is also known as the word problem for star-autonomous categories. Previous work has shown the problem
Heijltjes, Willem, Houston, Robin
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

"Boring formal methods" or "Sherlock Holmes deduction methods"?

open access: yes, 2016
This paper provides an overview of common challenges in teaching of logic and formal methods to Computer Science and IT students. We discuss our experiences from the course IN3050: Applied Logic in Engineering, introduced as a "logic for everybody ...
BF Sherman   +11 more
core   +1 more source

Representation results for defeasible logic [PDF]

open access: yes, 2000
The importance of transformations and normal forms in logic programming, and generally in computer science, is well documented. This paper investigates transformations and normal forms in the context of Defeasible Logic, a simple but efficient formalism ...
Antoniou, G.   +3 more
core   +7 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Hypersequents and the Proof Theory of Intuitionistic Fuzzy Logic [PDF]

open access: yes, 2000
Takeuti and Titani have introduced and investigated a logic they called intuitionistic fuzzy logic. This logic is characterized as the first-order Goedel logic based on the truth value set [0,1].
Baaz, Matthias, Zach, Richard
core   +4 more sources

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

open access: yesArthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah   +5 more
wiley   +1 more source

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