Results 71 to 80 of about 1,638,905 (280)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Participating in a Computer Science Linked-courses Learning Community Reduces Isolation [PDF]

open access: yesarXiv, 2017
In our previous work we reported on a linked-courses learning community for underrepresented groups in computer science, finding differences in attitudes and resource utilization between students in the community and other programming students. Here we present the first statistically significant differences in pre- to post-quarter student attitudes ...
arxiv  

Towards Accountable AI: Hybrid Human-Machine Analyses for Characterizing System Failure

open access: yes, 2018
As machine learning systems move from computer-science laboratories into the open world, their accountability becomes a high priority problem. Accountability requires deep understanding of system behavior and its failures. Current evaluation methods such
Horvitz, Eric   +2 more
core   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Learning unification-based grammars using the Spoken English Corpus [PDF]

open access: yesICGI-94 Colloquium, 1994
This paper describes a grammar learning system that combines model-based and data-driven learning within a single framework. Our results from learning grammars using the Spoken English Corpus (SEC) suggest that combined model-based and data-driven learning can produce a more plausible grammar than is the case when using either learning style isolation.
arxiv  

C-Sheep: Controlling Entities in a 3D Virtual World as a Tool for Computer Science Education [PDF]

open access: yes, 2006
One of the challenges in teaching computer science in general and computer programming in particular is to maintain the interest of students, who often perceive the subject as difficult and tedious. To this end, we introduce C-Sheep, a mini-language-like
Anderson, Eike F., McLoughlin, L.
core  

Machine learning for computational science and engineering models

open access: yes, 2017
Whitepaper submitted to the 2017 DOE ASCR Applied Math MeetingMachine learning for computational science and engineering modelsPaul Constantine, University of Colorado ...
openaire   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

A bright future for financial agent-based models

open access: yes, 2018
The history of research in finance and economics has been widely impacted by the field of Agent-based Computational Economics (ACE). While at the same time being popular among natural science researchers for its proximity to the successful methods of ...
Belianin, A.   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy