Results 91 to 100 of about 48,018,611 (257)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

CAD, BIM, GIS and other tricks of the computer science in the education of the Building Engineer

open access: yes, 2011
Revisione internazionale- relazione a invito- chair sessione S8T The paper aims to develop some thoughts on the upgrade implemented in the disciplines of drawing from the latest forms of digital representation, commenting on the experiences under way in some university courses included in the learning curriculum provided to engineering students with ...
NOVELLO, Giuseppa   +1 more
openaire   +1 more source

Computer-Supported Collaborative Production

open access: yes, 2006
This paper proposes the concept of collaborative production as a focus of concern within the general area of collaborative work. We position the concept with respect to McGrath's framework for small group dynamics and the more familiar collaboration ...
Yost, Beth   +4 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

5 Months of Haskell : Programming languages as just other programs. Contribution toward a field of computer science education.

open access: yes, 2019
The following is understood as a contribution toward a field of com-puter science education : a reflection of 5 months of learning the functionalprogramming language Haskell; out of which has emerged for us that pro-gramming languages are ‘just other programs’.
openaire   +2 more sources

UA66/3/2 Computer Science Alumni Newsletter, Vol. 6 [PDF]

open access: yes, 1991
Newsletter created by WKU Computer Science for alumni of the ...
WKU Computer Science
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A Practical One-Semester "VLSI Design" Course for Computer Science (and Other) Majors

open access: yes, 2007
This paper describes the development and content of a "VLSI Design" course. We had two main goals for the course: to develop a one-semester course for computer science (and other) majors, and to give the students practical experience with real ...
Robert Walker Kent   +3 more
core  

UA66/3/2 Computer Science Alumni Newsletter, Vol. 10 [PDF]

open access: yes, 1997
Newsletter created by WKU Computer Science for alumni of the ...
WKU Computer Science
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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