Results 51 to 60 of about 498,375 (267)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

CampProf: A Visual Performance Analysis Tool for Memory Bound GPU Kernels

, 2010
Current GPU tools and performance models provide some common architectural insights that guide the programmers to write optimal code. We challenge these performance models, by modeling and analyzing a lesser known, but very severe performance pitfall ...
Feng, Wu-chun, Aji, Ashwin M., Daga, Mayank   +2 more
core  

Breaking computational barriers : application of computational science on high performance computers

, 2016
The future of computational science is facing serious challenges: until recently, the computing power of processors was quickly increasing. However, physical limitations in the miniaturisation of computer chips halted this steady source of performance gains. Paradoxically, the computational cost of problems awaiting to be solved never stops to augment.
openaire   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Visualize This: Lessons from the Front-lines of High Performance Visualization

, 2020
This paper presents a comprehensive workflow to address two major factors in multivariate multidimensional (MVMD) scientific visualization: the scalability of rendering and the scalability of representation (for perception).
Mohammed, Ayat, Farrah, Duncan, Polys, Nicholas F.   +2 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Performance Evaluation of Navigation Approaches on High-resolution Displays

, 2007
We conducted a study to discover if the data navigation techniques suitable for high-resolution displays differed significantly from those traditionally used for single-screen desktop displays.
Montabert, Cyril, Tungare, Manas, Menon, Suraj, North, Christopher L.   +3 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A guide to Macro and Micro Computer Performance Evaluation. [PDF]

, 1983
Guidelines and discussions are presented for computer performance evaluation at two levels. The first level, Computer Performance Management (CPM) or Macro Performance Evaluation, involves an overall computer performance management strategy ...
Gray, Gary Kenneth.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source