FEBS Open Bio, EarlyView.Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi +5 more
wiley +1 more source
Capybara: Efficient estimation of generalized linear models with high-dimensional fixed effects. [PDF]
PLoS OneSepulveda MV.
europepmc +1 more source
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
FEBS Open Bio, EarlyView.This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma +10 more
wiley +1 more source
Evolving funding strategies for research software: Insights from an international survey of research funders. [PDF]
PLoS OneJensen EA, Katz DS.
europepmc +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
FEBS Open Bio, EarlyView.A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
Fundamental Solutions to Fractional Heat Conduction in Two Joint Half-Lines Under Conditions of Nonperfect Thermal Contact. [PDF]
Entropy (Basel)Povstenko Y +3 more
europepmc +1 more source
Computer Science & Software Engineering : Proceedings of the 1st Student Workshop (CS&SE@SW 2018), Kryvyi Rih, Ukraine, November 30, 2018 [PDF]
, 2018 openalex +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
Exploring the consistency, quality and challenges in manual and automated coding of free-text diagnoses from hospital outpatient letters. [PDF]
PLoS OneDel-Pinto W +9 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu +8 more
wiley +1 more source