Results 41 to 50 of about 1,719,777 (299)

Imagine All the People: Citizen Science, Artificial Intelligence, and Computational Research

open access: yes, 2021
Machine learning, artificial intelligence, and deep learning have advanced significantly over the past decade. Nonetheless, humans possess unique abilities such as creativity, intuition, context and abstraction, analytic problem solving, and detecting unusual events.
Shanley, Lea A.   +4 more
openaire   +2 more sources

Computational philosophy of science [PDF]

open access: yesarXiv, 2023
Philosophy of science attempts to describe all parts of the scientific process in a general way in order to facilitate the description, execution and improvements of this process. So far, all proposed philosophies have only covered existing processes and disciplines partially and imperfectly.
arxiv  

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Grand Challenges in Computational Materials Science: From Description to Prediction at all Scales [PDF]

open access: yesFrontiers in Materials, 2014
TRADITIONAL COMPUTATIONAL MATERIALS SCIENCE Materials science is historically linked to engineering driven by the need of materials with specific properties to manufacture infrastructure, machines, and devices. Therefore, there has always been a need for novel and better materials: stronger and lighter-weight, less expensive, easier to process, more ...
openaire   +3 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Challenges of Computer Science and IT in Teaching-Learning in Saudi Arabia

open access: yesSukkur IBA Journal of Computing and Mathematical Sciences, 2018
Personal Computers (PCs) have invaded all ranges of civilization and there is currently a reasonable connection among technology, development and economic persistence.
Dr. Hafiz Abid Mehmood Malik   +3 more
doaj   +5 more sources

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

Computer-Assisted Teaching in Science Education: A Bibliometric Overview

open access: yesJournal of Science Learning
This study aims to examine the studies on computer-assisted teaching in science teaching in terms of different variables with bibliometric analysis. Scopus database was used to collect the data.
Meryem Konu Kadirhanoğulları
doaj   +1 more source

Machine learning, meaning making: On reading computer science texts

open access: yesBig Data & Society, 2023
Computer science tends to foreclose the reading of its texts by social science and humanities scholars – via code and scale, mathematics, black box opacities, secret or proprietary models.
Louise Amoore   +3 more
doaj   +1 more source

Science Education in the 21st Century [PDF]

open access: yesNature Astronomy 2018, 2, 530-533, 2018
The traditional university science curriculum was designed to train specialists in specific disciplines. However, in universities all over the world, science students are going into increasingly diverse careers and the current model does not fit their needs. Advances in technology also make certain modes of learning obsolete.
arxiv   +1 more source

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