Results 71 to 80 of about 4,042,014 (292)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

An investigation into the use of e-assessment to support student learning [PDF]

, 2009
Interactive computer-marked assessment has been incorporated into a range of science courses at the UK Open University. Different question types have been used, but all allow students multiple attempts so as to enable them to act on the feedback provided.
Jordan, Sally
core  

A survey of comics research in computer science

, 2018
Graphical novels such as comics and mangas are well known all over the world. The digital transition started to change the way people are reading comics, more and more on smartphones and tablets and less and less on paper.
Augereau, Olivier, Iwata, Motoi, Kise, Koichi   +2 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Computer, Computer Science, and Computational Thinking: Relationship between the Three Concepts

Human Behavior and Emerging Technologies
Digital computers were invented in the 1940s. They are sophisticated and versatile machines whose functioning is grounded in elaborate theory. Advances in theory and the availability of computers helped computer science to develop as an academic ...
Pinaki Chakraborty
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Women, AI, and the Power of Supporting Communities: A Digital Gender-Support Partnership

Patterns, 2020
With the rapid development of the fields of data science and artificial intelligence, a dichotomy presents itself: more professionals are needed to fulfill the growing workfoce demand, and women continue to be underrepresented in all computer science ...
Judith Cerit, Azadeh Dindarian, Naz Cilo-van Norel   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Reconfigurable Optical Frequency Comb and Nyquist Pulses Generation With Tunable Sensitivities

IEEE Access, 2020
In this paper, a practical scheme to achieve reconfigurable optical frequency comb (OFC) and Nyquist pulses generation based on two cascaded Mach-Zehnder modulators and a polarization control structure is theoretically analyzed and verified by simulation.
Hongyao Chen, Jianping Wang, Huimin Lu, Tigang Ning, Li Pei, Jing Li   +5 more
doaj   +1 more source