Results 131 to 140 of about 32,982,640 (297)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

A game-theoretic sequential three-way decision using probabilistic rough sets and multiple levels of granularity

open access: yesDiscover Computing
The sequential three-way decision accepts additional information at each level and makes more accurate definite decisions with less uncertainty. This process can also be extended to two-way classification with the finer-grained information level. However,
T. V. Soumya, M. K. Sabu
doaj   +1 more source

Proceedings of the Second Annual Virginia Tech Center for Human-Computer Interaction Research Experience for Undergraduates (REU) Symposium

open access: yes, 2008
Virginia Tech's Center for Human-Computer Interaction presents the project abstracts for the REU ’07 symposium. The REU (Research Experience for Undergraduates) program provides undergraduate students from various universities with the opportunity to ...
Coordinator, REU
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Explainable feature selection using improved firefly algorithm with population diversification and stagnation-aware exploration

open access: yesDiscover Computing
Feature selection is an important preprocessing step in classification. By reducing dimensionality and removing irrelevant features, it can help improve classification performance.
M. G. Bindu, S. Malathi
doaj   +1 more source

UA66/3/2 Computer Science Alumni Newsletter, Vol. 6 [PDF]

open access: yes, 1991
Newsletter created by WKU Computer Science for alumni of the ...
WKU Computer Science
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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