Results 51 to 60 of about 307,993 (262)

Quantifying Recent State-of-Arts for Breast Cancer Segmentation, Detection and Classification: A Review [PDF]

E3S Web of Conferences
Researchers have been motivated to create effective, dependable, and scalable computer-aided diagnostic (CAD) systems given the rising incidence of breast cancer and its high death rates.
Chintakunta Job Prasanth Kumar, Lepakshi Vijayalakshmi A.   +1 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Analyzing the Accuracy of Clustering Based Cab Recommender System (CBCRS) Across Varying Densities [PDF]

International Journal of Mathematical, Engineering and Management Sciences
Recommender systems are widely used in today’s world as they narrow down a huge number of options for a user in various fields. These recommender systems can also be significantly used by cab drivers also, since they can recommend the nearest location of
Supreet Kaur Mann, Sonal Chawla
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Reliability with multiple causes of failures: Modeling and practice through a case study on ultrasound probes for medical imaging

International Journal of Metrology and Quality Engineering
In this paper, we deal with statistical modeling and a related case study for reliability when multiple failure causes are present. At first, we present in detail two main approaches for competing risk modeling, e.g.
Berni Rossella, Bertocci Francesco, Magrini Alessandro, Nikiforova Nedka D.   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Deep vision in agriculture: assessing the function of YOLO in the classification of plant leaf diseases (PLDs)

BioData Mining
Plant leaf diseases (PLDs) can continue to be a significant problem in the agricultural sector, leading to significant losses in production and jeopardizing food security.
Chhaya Gupta, Nasib Singh Gill, Preeti Gulia, Sangeeta Duhan, Noha Alduaiji, Piyush Kumar Shukla, Abhishek Dwivedi   +6 more
doaj   +1 more source