Results 271 to 280 of about 1,917,413 (346)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The mental health benefit of a community-based home-visiting program for prenatal women: evidence from a randomized controlled trial in China. [PDF]

BMC Pregnancy Childbirth
Wang N, Li B, Yang J, Liu Z, Shi Y, Nie J.   +5 more
europepmc   +1 more source

Computer science education: today and tomorrow [PDF]

, 2014
Mykhailovych, Taras
core  

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Fostering Multidisciplinary Collaboration in Artificial Intelligence and Machine Learning Education: Tutorial Based on the AI-READI Bootcamp.

JMIR Med Educ
Nishihara TW, Kalaw FGP, Engmann A, Motoyoshi A, Mensah-Kane P, Gupta D, Patronilo V, Zangwill LM, Hallaj S, Panahi A, Cottrell GW, Voytek B, de Sa VR, Baxter SL.   +13 more
europepmc   +1 more source

Measurement Properties of Instruments Assessing Digital Competence in Nursing: A Systematic Review. [PDF]

Appl Clin Inform
D'Agostino F, Erba I, Ammenwerth E, Robinzon V, Segal G, Harel N, Corvo E, Barkan R, Lewy H, Giannetta N.   +9 more
europepmc   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

An Analysis of the School Catering Management System of Thailand Through HiAP's Four Pillars. [PDF]

Health Promot J Austr
Mathurapote N, Posayanonda T, Sae-Iew K.
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

System log anomaly detection based on contrastive learning and retrieval augmented. [PDF]

Sci Rep
Li W, Wu Y, Huang W, Zhou F, Ou W, Wang H, Deng L.   +6 more
europepmc   +1 more source