Results 61 to 70 of about 659,160 (268)

Computational protocol for modeling and analyzing synaptic dynamics using SRPlasticity

STAR Protocols
Summary: Transient changes in synaptic strength, known as short-term plasticity (STP), play a fundamental role in neuronal communication. Here, we present a protocol for using SRPlasticity, a software package that implements a computational model of STP.
Jade Poirier, John Beninger, Richard Naud   +2 more
doaj   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Protocol for using Multiomics2Targets to identify targets and driver kinases for cancer cohorts profiled with multi-omics assays

STAR Protocols
Summary: The availability of multi-omics data applied to profile cancer cohorts is rapidly increasing. Here, we present a protocol for Multiomics2Targets, a computational pipeline that can identify driver cell signaling pathways, protein kinases, and ...
Giacomo B. Marino, Eden Z. Deng, Daniel J.B. Clarke, Ido Diamant, Adam C. Resnick, Weiping Ma, Pei Wang, Avi Ma’ayan   +7 more
doaj   +1 more source

Periodismo de precisión: el método socioinformático de investigación de la actualidad / The precision journalism: the socio-computer approach of today research [PDF]

Comunicación y Hombre, 2009
El periodismo de precisión es una especialidad, a caballo entre el periodismo de investigación y elperiodismo científico, que permite a los medios de comunicación prestar mayor y mejor atención aproblemas importantes, utilizando métodos adecuados para ...
Homero Valencia Benito
doaj  

Computer science and technology : historiography VII (9)

, 2022
Camille Akmut
openalex   +2 more sources

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Protocol for UAV fault diagnosis using signal processing and machine learning

STAR Protocols
Summary: Unmanned aerial vehicles (UAVs) require fault diagnosis for safe operation. Here, we present a protocol for UAV fault diagnosis using signal processing and artificial intelligence.
Luttfi A. Al-Haddad, Alaa Abdulhady Jaber, Nibras M. Mahdi, Sinan A. Al-Haddad, Mustafa I. Al-Karkhi, Zainab T. Al-Sharify, Ahmed Ali Farhan Ogaili   +6 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Protocol to perform integrative analysis of high-dimensional single-cell multimodal data using an interpretable deep learning technique

STAR Protocols
Summary: The advent of single-cell multi-omics sequencing technology makes it possible for researchers to leverage multiple modalities for individual cells.
Manqi Zhou, Hao Zhang, Zilong Bai, Dylan Mann-Krzisnik, Fei Wang, Yue Li   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source