Results 161 to 170 of about 3,360,768 (285)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Supporting files for "WingAnalogy: A Software Tool for High-Precision Measurement of Insect Wing Fluctuating Asymmetry using Computer Vision and Particle Swarm Optimization"

, 2023
Shahab Eshghi, Hamed Rajabi, Lisa Claußen, Johannes Poser, Thies H. Büscher, Stanislav N. Gorb   +5 more
openalex   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Recent advancements in computer & software technology. [PDF]

ScientificWorldJournal, 2014
Mishra KK, Misra AK, Mueller P, Martinez Perez G, Bhatia SK, Wang Y.   +5 more
europepmc   +1 more source

Mitiq: A software package for error mitigation on noisy quantum computers [PDF]

, 2022
Ryan LaRose, Andrea Mari, Peter J. Karalekas, Nathan Shammah, William J. Zeng, Piotr Czarnik, Mohamed El Mandouh, Max H. Gordon, Yousef Hindy, Aaron Robertson, Purva Thakre, Misty Wahl, Danny Samuel, Rahul Mistri, Maxime Tremblay, Nick Gardner, Nathaniel T. Stemen, Nathan Shammah, William J. Zeng   +18 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Exploratory study to examine the neuroendocrinological changes in typically developing adults during a music-related participatory practice using computer software. [PDF]

Front Psychol
Sugiyama Y, Tanaka S, Komagome A, Yuhi T, Furuhara K, Higashida H, Tsuji T, Kikuchi M, Tsuji C.   +8 more
europepmc   +1 more source

A diagnostic tool for malaria based on computer software. [PDF]

Sci Rep, 2015
Kotepui M, Uthaisar K, Phunphuech B, Phiwklam N.   +3 more
europepmc   +1 more source

Methods for plotting function graphs in computers using modern software and programming languages

, 2021
Sh. Q. Shoyqulov, A. A. Bozorov
openalex   +1 more source