Results 51 to 60 of about 21,327,351 (253)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A computer‐aided continuous assessment system [PDF]

open access: yes, 1996
A high‐quality assessment system should have the following attributes: rapid feedback to the students, appropriate and detailed feedback, and an effective grading system which provides an accurate overall grade as well as information which identifies the
Turton, B. C. H., B. C.H. Turton
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

CGIAR System Annual Performance Report Data 2017-2021 - Partnerships

open access: yes, 2019
A Partnership is a recognized relationship between a CRP and another institution/institutions external to CGIAR, to jointly undertake activities that contribute to each institution's mandate.
System Organization, CGIAR
core   +1 more source

Elements of control theory to provide in-depth training to computer

open access: yesRUDN Journal of Informatization in Education, 2011
In this article the implementation of basic management functions in-depth study computer science. Systematic approach in managing the organization of teaching informatics system consists of determining the content of your course of study computer science
O Yu Zaslavskaya, N I Filatova
doaj  

COMMUNICATIONS IN MANAGEMENT SYSTEMS

open access: yesВестник университета, 2018
In the modern world, information exchange is becoming dominant. Information is one of the main resources in the management system and the eectiveness of communication interactions directly aects the life activity of the organization. The most common form
N. Efimochkina
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Digital Logic and Computer Organization

open access: yes, 2004
CSC 242. Digital Logic and Computer Organization (3) Prerequisite: CSC 133. Corequisite: CSC 241. Study of computer system organization; combinational and sequential circuit analysis and synthesis; register-transfer language and microprogramming ...
Tompkins, Jack
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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