Results 81 to 90 of about 1,778,148 (300)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Organization of the channel-switching process in parallel computer systems based on a matrix optical switch [PDF]
After a classification and analysis of electronic and optoelectronic switching devices, the design principles and structure of a matrix optical switch is described.
Golomidov, Y. V. +3 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Pelaksanaan Kontrol dan Audit Sistem Informasi pada Organisasi [PDF]
, 2005 Information system auditing is a function that has been developed to assess whether computer systems safeguard assets, maintain data integrity, and allow the goals of an organization to be achived effectively and efficiently.
Imbar, R. V. (Radiant)
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Les Technopères : la carte informatique, un chemin initiatique
ReS Futurae, 2017 The eight-parts saga of the comic strip Les Technopères (1998-2006) by Jodorowsky, Beltran and Janjetov depicts a rich representation of computer science in the beginning of the story. Inspired by a cyberpunk background, the story can be read, on the one
Eric Villagordo
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Artificial intelligence in safety system
MATEC Web of Conferences, 2018 This research aims to study learning environment, and let the learning environment become smart. Swarm intelligence, cloud computing, and active Ultra-High Frequency RFID were used on it.
Chen Li-Shan +2 more
doaj +1 more source