Results 51 to 60 of about 743,425 (266)

Computational Systems Biology [PDF]

The Scientific World Journal, 2013
The complex biological systems consist of distinct molecules that exert their functions by interacting with each other, which makes it a big challenge to understand how the cellular machinery works. Recently, the accumulation of a large amount of multiscale omics data, such as next-generation sequencing data and protein interaction data, provides ...
Xing-Ming Zhao, Weidong Tian, Rui Jiang, Jun Wan   +3 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Belle computing system [PDF]

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2004
We describe the present status of the computing system in the Belle experiment at the KEKB $e^+e^-$ asymmetric-energy collider. So far, we have logged more than 160 fb$^{-1}$ of data, corresponding to the world's largest data sample of 170M $B\bar{B}$ pairs at the $Υ(4S)$ energy region.
Ichiro Adachi, Taisuke Hibino, Luc Hinz, Ryosuke Itoh, Nobu Katayama, Shohei Nishida, Frederic Ronga, Toshifumi Tsukamoto, Masahiko Yokoyama   +8 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Bi-Level Optimization in a Transport Network

Cybernetics and Information Technologies, 2015
This paper applies a bi-level formalism for the optimal control of an urban transportation network. The well known store-and-forward model in traffic control is utilized in order to increase the control space of the optimization problem.
Stoilov Todor, Stoilova Krasimira, Papageorgiou Markos, Papamichail Ioannis   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protection of Information Resources of Computer Systems as a System of Performance Data Protection

Безопасность информационных технологий, 2011
System solutions of actual problems of information security of computer systems is achieved by a comprehensive analysis of existing approaches to the protection of computer information.
V. K. Dzhogan, A. P. Kurylo
doaj  

Implementation of the Numbered Heads Together Learning Model to Improve Students’ Learning Outcomes

Jurnal Inovasi Pendidikan dan Sains
This study aims to determine how the implementation of the Numbered Heads Together (NHT) learning model contributes to the improvement of students’ learning outcomes.
Putri Suri Anjani, Celine Aloyshima Haris   +1 more
doaj   +1 more source

Remote Design and Manufacture through the Example of a Ventilator

Applied Sciences, 2020
In this paper, the authors present a completely new approach to the remote prototyping process, taking into account the distributed nature of design and manufacturing resources. A new model is suggested, taking into account the conditions of the Industry
Andrzej Paszkiewicz, Marek Bolanowski, Grzegorz Budzik, Piotr Sowa, Tomasz Pisz, Mariusz Oleksy, Łukasz Przeszłowski   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source