Results 51 to 60 of about 12,647,201 (315)
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
SOLVING THE BENJAMIN-BON-MAHONEY EQUATION IN A SPECIAL CASE BY NUMERICAL METHODS [PDF]
The Benjamin-Bon-Mahoney equation is the most common equation in scientific research. This equation is often used in hydrodynamics, nonlinear optics, and acoustics, because the equation is nonlinear, so its analytical solution is very difficult.
Dyushebaeva A. +3 more
doaj +1 more source
A pragmatic critique of the conception of everyday praxis within Jeffrey Alexander’s cultural sociology [PDF]
This paper tries to critically analyse Jeffrey Alexander’s cultural sociology. In the first part of the paper I will examine Alexander’s conception of hermeneutical structuralism which argues that conventional systemic sociology and richness of ...
Prodanović Srđan
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Discovering the patterns of human-environment interactions using scalable functional textiles
Thesis: S.M., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, May, 2020Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (pages 59-63).Humans perform complex tasks
Luo, Yiyue(Computer scientist)Massachusetts Institute of Technology.
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Introduction. The main attention is paid to the need to take into account estimates of rounding errors when solving problems of transcomputational complexity.
Valerii Zadiraka, Inna Shvidchenko
doaj +1 more source

