Results 121 to 130 of about 32,367 (309)

Safe operations of a reach stacker by computer vision in an automated container terminal

open access: yesAlexandria Engineering Journal
Smart ports, utilizing advanced and hybrid technologies, are gaining increasing attention for application in the maritime industry, with driver assistance and autonomous driving being pivotal in container-terminal operations.
Truong Ngoc Cuong   +6 more
doaj   +1 more source

A Portable Piezoelectric Tactile Terminal for Braille Readers

open access: yesApplied Bionics and Biomechanics, 2012
This paper introduces a novel concept on reading assistive technologies for the blind: the TactoBook, a system that is able to translate entire electronic books (eBooks) to Braille code and to reproduce them in portable electronic Braille terminals.
Ramiro Velázquez   +2 more
doaj   +1 more source

On Termination of Logic Programs with Floating Point Computations

open access: yes, 2002
Numerical computations form an essential part of almost any real-world program. Traditional approaches to termination of logic programs are restricted to domains isomorphic to N, more recent works study termination of integer computations. Termination of computations involving real numbers is cumbersome and counter-intuitive due to rounding errors and ...
Serebrenik, Alexander, De Schreye, Danny
openaire   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Confluence of Terminating Rewriting Computations

open access: yes, 2023
Rewriting is an intentional model of computation which is inherently non-deterministic. Defining functions by rewriting requires to prove that the result of a given computation is unique for every input, a property called confluence. This chapter describes confluence criteria for first-order as well as higher-order, terminating rewriting computations ...
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Secure multiparty computation between distrusted networks terminals [PDF]

open access: yes
One of the most important problems facing any distributed application over a heterogeneous network is the protection of private sensitive information in local terminals.
Nguyen, Thinh, Cheung, S.-C. S.
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

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