Results 1 to 10 of about 11,849 (212)

French trainers’ beliefs on problems and computing [PDF]

open access: yesITM Web of Conferences, 2021
We present an exploratory research based on an online questionnaire to better understand the French trainers’ beliefs on problems and computing from grades 1 to 3 of primary school. We explain the French context of the new 2016 curriculum and of the 2018 report on mathematics teaching that motivates the content and the interest of the questionnaire ...
Cabassut Richard, Simard Arnaud
openaire   +2 more sources

COMPUTED TORQUE CONTROL FOR A SPATIAL DISORIENTATION TRAINER [PDF]

open access: yesFacta Universitatis, Series: Mechanical Engineering, 2020
A development of a robot control system is a highly complex task due to nonlinear dynamic coupling between the robot links. Advanced robot control strategies often entail difficulties in implementation, and prospective benefits of their application need to be analyzed using simulation techniques.
Vidaković, J.   +3 more
openaire   +3 more sources

Computer Karate Trainer in Tasks of Personal and Homeland Security Defense [PDF]

open access: yes, 2013
In this paper will be presented a new possibility of using GDL (Gesture Description Language) approach for recognition of basic combat techniques from martial arts. The GDL approach allows not only to analyze the several Shorin-Ryu Karate techniques but also to support the training and teaching activities of such arts. Moreover the GDL allow performing
Tomasz Hachaj, Marek R. Ogiela
openaire   +2 more sources

Computer trainers as a tool to overcome difficulties in learning mathematics

open access: yesPedagogical Review, 2023
Дефицит рабочей памяти рассматривается как основная причина трудностей в усвоении математики. Для преодоления трудностей в усвоении математики предлагаются компьютерные тренажеры рабочей памяти на основе математического контента. Если тренажеры не имеют математической составляющей, а направлены лишь на улучшение работы основных компонентов рабочей ...
openaire   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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