Results 31 to 40 of about 6,532 (267)

Variation in clinical coding lists in UK general practice: a barrier to consistent data entry?

Journal of Innovation in Health Informatics, 2007
Background Routinely collected general practice computer data are used for quality improvement; poor data quality including inconsistent coding can reduce their usefulness.
Tracy Waize, Sobanna Anandarajah, Neil Dhoul, Simon de Lusignan   +3 more
doaj   +1 more source

Routinely-collected general practice data are complex, but with systematic processing can be used for quality improvement and research

Journal of Innovation in Health Informatics, 2006
Background UK general practice is computerised, and quality targets based on computer data provide a further incentive to improve data quality. A National Programme for Information Technology is standardising the technical infrastructure and removing ...
Simon de Lusignan, Nigel Hague, Jeremy VanVlymen, Pushpa Kumarapeli   +3 more
doaj   +1 more source

Recording COVID-19 consultations: review of symptoms, risk factors, and proposed SNOMED CT terms

BJGP Open, 2020
Background: There is an urgent need for epidemiological research in primary care to develop risk assessment processes for patients presenting with COVID-19, but lack of a standardised approach to data collection is a significant barrier to implementation.
Bhautesh Dinesh Jani, Jill P Pell, Dylan McGagh, Harshana Liyanage, Dave Kelly, Simon de Lusignan, Christopher J Weatherburn, Ronnie Burns, Frank M Sullivan, Frances S Mair   +9 more
doaj   +1 more source

Availability of Computerised Medical Record System Data to Compare Models of Child Health Care in Primary Care Across Europe

, 2017
Computerised medical record (CMR) system data can be used to compare different models of health care for children. We identified sources of data from the Models of Child Health Appraised (MOCHA) project that compares family doctor led with paediatrician led and mixed models of child care using index conditions.
Liyanage, H, Hoang, U, Ferreira, F, Alexander, D, Rigby, M, Blair, M, De Lusignan, S   +6 more
openaire   +3 more sources

Development of a database for cervical cytology reports

Journal of Innovation in Health Informatics, 2011
Background Cervical cancer is an important cause of female mortality. Its incidence, however, has been drastically reduced by early detection using the Papanicolaou screening method.
Eduardo Dreizzen, María Lima, Rosa Kitagawa, Félix Corrons, Osvaldo Spinelli   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Modelling Access Control For Healthcare Information Systems [PDF]

, 2007
The widening use of Information Systems, which allow the collection, extraction, storage, management and search of information, is increasing the need for information security.
Ferreira, Ana, Antunes, Luis, Chadwick, David W.   +2 more
core  

Large-scale implementation and adoption of the Finnish national Kanta services in 2010–2017: a prospective, longitudinal, indicator-based study

Finnish Journal of eHealth and eWelfare, 2018
In Finland, implementation and adoption of the national Kanta services’ second phase services were carried out step-by-step from May 2010 till December 2017. The Kanta services currently include integrated, interoperable health information from EMR, EHR,
Vesa Jormanainen
doaj   +1 more source

The STORK dataset: Linked midwifery and delivery records of the mothers and index children in the Avon Longitudinal Study of Parents and Children (ALSPAC) [version 1; peer review: 2 approved]

Wellcome Open Research, 2020
This data note describes the linked antenatal and delivery records of the mothers and index children of the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort study.
Mark Mummé, Andy Boyd, Jean Golding, John Macleod   +3 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source