Results 51 to 60 of about 417,879 (291)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Frontiers in Microbiology, 2022 This pilot study was designed to identify the salivary microbial community and metabolic characteristics in patients with generalized periodontitis. A total of 36 saliva samples were collected from 13 patients with aggressive periodontitis (AgP), 13 ...
Yiping Wei +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Cognitive Rehabilitation in Schizophrenia-Associated Cognitive Impairment: A Review
Neurology International, 2022 Patients suffering from schizophrenia often experience cognitive disturbances. Cognitive rehabilitation—computerized or non-computerized—is widely known as an alternative way to enhance cognitive functioning in patients with schizophrenia. The aim of the
Elli Zoupa +7 more
doaj +1 more source
Brazilian Journal of Information Science: research trends, 2011 This paper is a recent ontological view of the concept of library computerization at a global perspective. The paper not only saliently x-rayed the processes involved with library computerization but also provided insight to the advantageous effect the novel trend has in eradicating illiteracy and promoting educational development through efficient ...
openaire +4 more sources
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Clinical Interventions in Aging, 2013 Grace Y Lee,1 Calvin CK Yip,2 Edwin CS Yu,3 David WK Man4 1Occupational Therapy Department, Kwai Chung Hospital, 2CY Functional Recovery Services, 3Psychogeriatric Team, Kwai Chung Hospital, 4Department of Rehabilitation Sciences, the Hong Kong ...
Lee GY, Yip CC, Yu EC, Man DW
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Improvement of upsetting process of four-beam workpieces based on computerized and physical modeling [PDF]
FME Transactions, 2020 The method of upsetting of large ingots has been investigated in this work. The proposed method consists in upsetting of profiled workpieces with concave faces. An angle of the concave faces was 150°. A relative depth of the concave faces has been varied
Markov Oleg E. +5 more
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