Results 51 to 60 of about 290,815 (312)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Computerized Test Construction [PDF]
, 2015 This article starts with a brief introduction to the area of computerized test construction. In the first section, the problem is formally stated as an optimization problem, with an objective function, for example, that maximizes the amount of ...
Veldkamp, Bernard P.; id_orcid +1 more
core +3 more sources
Contextual Topic Modeling of Persian Social Media Short Texts [PDF]
پژوهشهای نظری و کاربردی هوش ماشینیThe emergence of social media creates opportunities for users to share their thoughts. Billions of short texts are produced on social media daily, and their analysis in text mining and content analysis is essential. Detecting topics from short texts on a
Zeynab Mottaghinia +1 more
doaj +1 more source
Frontiers in Microbiology, 2022 This pilot study was designed to identify the salivary microbial community and metabolic characteristics in patients with generalized periodontitis. A total of 36 saliva samples were collected from 13 patients with aggressive periodontitis (AgP), 13 ...
Yiping Wei +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
IMPACT OF PRODUCT QUALITY ON LEVEL OF CUSTOMER SATISFACTION IN SLEEPOLIC BANDUNG E-COMMERCE
Journal of Management Small and Medium Enterprises (SME's)The objective of this study is to evaluate the effect of product quality on customer satisfaction at Sleepolic e-commerce platform in Bandung and to identify potential strategies for improving customer satisfaction.
Neng Wulandari, Tiris Sudrartono
doaj +1 more source
Computerized Energy Information Sources [PDF]
, 1979 Many computerized files of energy- and energy conservation-related information are currently available through commercial and governmental sources such as Lockheed Information Systems, System Development Corporation, and DOE/RECON. Private, governmental,
Gordon, D.
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Improvement of upsetting process of four-beam workpieces based on computerized and physical modeling [PDF]
FME Transactions, 2020 The method of upsetting of large ingots has been investigated in this work. The proposed method consists in upsetting of profiled workpieces with concave faces. An angle of the concave faces was 150°. A relative depth of the concave faces has been varied
Markov Oleg E. +5 more
doaj
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source