Results 61 to 70 of about 121,162 (309)

The institutional character of computerized information systems [PDF]

, 1989
We examine how important social and technical choices become part of the history of a computer-based information system (CB/SJ and embedded in the social structure which supports its development and use.
Iacono, Suzanne, Kling, Rob
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Acute mixed vestibulopathy. History case from the vestibulologist practice. Case report

Consilium Medicum, 2023
Patients with acute vestibulopathy are among the most uneasy (in terms of severity of symptoms) and challenging (in terms of determining the level of damage).
Sergei V. Lilenko, Dmitry S. Luppov
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

The Spanish version of the computerized dynamic test of analogical reasoning

Acta Psychologica
Purpose: Analogical reasoning (AR), a key skill developing throughout childhood, enables the transfer of relational structures across contexts, facilitating the integration of new knowledge with prior understanding.
Isabel Monte-Tablada, Macarena de los Santos-Roig, Sergio Moreno-Ríos, Bart Vogelaar, Francisca Serrano, Sara Mata   +5 more
doaj   +1 more source

Role of newer imaging modalities for airway assessment in dynamic tracheal compression

Journal of Anaesthesiology Clinical Pharmacology, 2014
Anesthetic management of a patient with tracheal stenosis is challenging. Though we have newer imaging modalities like multislice, three-dimensional computerized tomography, virtual bronchoscopy to determine the size and anatomy of the airway, it is ...
Prabha Udayakumar, Madhurima Srikanti, Vinodhadevi Vijayakumar, Gunavathi Kandappan   +3 more
doaj   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

A validation of mobile sensing actigraphy devices for generating a biomechanical model of posture [PDF]

, 2017
Mobile sensing actigraphy was tested and validated as a modality for computing dynamic posturography. Twelve healthy volunteer subjects (6 male) were administered risperidone and assessed for postural stability using a NeuroCom® Balance Master system and
Detheridge, Craig Neal
core   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Large Language Model-Driven Dynamic Assessment of Grammatical Accuracy in English Language Learner Writing

IEEE Access
This study investigates the potential for Large Language Models (LLMs) to scale-up Dynamic Assessment (DA). To facilitate such an investigation, we first developed DynaWrite—a modular, microservices-based grammatical tutoring application which ...
Timur Jaganov, John Blake, Julian Villegas, Nicholas Carr   +3 more
doaj   +1 more source