Strengths and weaknesses of computerized clinical decision support systems: insights from a digital control center (C3 COVID-19) for early and personalized treatment for COVID-19. [PDF]
Aiello TF+11 more
europepmc +1 more source
NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi+16 more
wiley +1 more source
Mitigating Risks in Hospital Stock Management: A Structured Method for Validating Excel Files. [PDF]
Gaoual Y+5 more
europepmc +1 more source
The oncogenic ETS factor ETV4 exerts a pleiotropic control over DNA replication both in a transcription‐dependent and ‐independent fashion in NSCLC cells. High‐ETV4 expression leads to R‐loop formation and DNA damage in response to TOP1 inhibition.
Jiaxi Zhang+14 more
wiley +1 more source
Narrative Review of Electronic Health Record Systems in Anesthesia: Benefits, Risks, and Medico-Legal Considerations in the United States of America. [PDF]
Tewfik G+6 more
europepmc +1 more source
A soft poly (3,4‐ethylenedioxythiophene):poly (styrenesulfonate)‐based electrode enables continuous, high‐quality recording of peripheral nerve activity. A neural network model integrating handcrafted and convolutional neural network‐based features decodes whisker movements with strong generalization, offering insights into peripheral nerve function ...
Liangpeng Chen+22 more
wiley +1 more source
Identifying Asthma-Related Symptoms From Electronic Health Records Using a Hybrid Natural Language Processing Approach Within a Large Integrated Health Care System: Retrospective Study. [PDF]
Xie F+9 more
europepmc +1 more source
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia+29 more
wiley +1 more source
Neonatal outcome in late preterm twin gestation: impact of antenatal corticosteroids therapy before 34 weeks. [PDF]
Eliner O+5 more
europepmc +1 more source