Results 131 to 140 of about 5,169,614 (387)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Discrete Cosine Transforms on Quantum Computers [PDF]

, 2001
A classical computer does not allow to calculate a discrete cosine transform on N points in less than linear time. This trivial lower bound is no longer valid for a computer that takes advantage of quantum mechanical superposition, entanglement, and ...
Klappenecker, Andreas, Roetteler, Martin
core   +2 more sources

THE ATTITUDES OF TEACHERS AND SPECIAL EDUCATORS TOWARDS THE USE OF COMPUTERS AND MODERN TECHNOLOGY IN TEACHING CHILDREN WITH DEVELOPMENTAL DISABILITIES

Research in Education and Rehabilitation
The goal of education is to provide favorable conditions for creativity, cooperation, actualization, and flexibility in order to prepare students for active work and functioning in society. This is especially important for inclusive education as students
Aleksandra Bašić, Dragana Maćešić Pterović, Bojana Arsić   +2 more
doaj   +1 more source

Establishing the European Norm for the health-related quality of life domains of the computer-adaptive test EORTC CAT Core [PDF]

, 2018
Gregor Liegl, Morten Aagaard Petersen, M. Groenvold, Neil K Aaronson, Anna Costantini, Peter Fayers, Bernhard Holzner, C. Daniel Johnson, Georg Kemmler, K Tomaszewski, Annika Waldmann, T. Young, Matthias Rose, Sandra Nolte   +13 more
openalex   +1 more source

Recent developments on computer aided systems for diagnosis of diabetic retinopathy: a review [PDF]

, 2022
Shradha Dubey, Manish Dixit
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Barriers to the Use of Serious Computer Games in the Practical Work with Children with Educational Difficulties [PDF]

, 2021
Margarita Stankova, Daniela Tuparova, Georgi Tuparov, Polina Mihova   +3 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Common data buffer system [PDF]

, 1981
A high speed common data buffer system is described for providing an interface and communications medium between a plurality of computers utilized in a distributed computer complex forming part of a checkout, command and control system for space vehicles
Byrne, F.
core   +1 more source

Automatic Gully Detection: Neural Networks and Computer Vision [PDF]

, 2020
Artur Gafurov, Oleg Yermolayev
openalex   +1 more source