Results 231 to 240 of about 5,169,614 (387)

Correction: Climate change prediction in Saudi Arabia using a CNN GRU LSTM hybrid deep learning model in al Qassim region. [PDF]

Sci Rep
Elabd E, Hamouda HM, Ali MAM, Fouad Y.
europepmc   +1 more source

Pre-Service Computer Teachers’ Tendencies Towards the Use of Mobile Technologies: A Technology Acceptance Model Perspective [PDF]

, 2017
Ünal Çakıroğlu, Seyfullah Gökoğlu, Mücahit Öztürk   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Developing a quantum computing model for sequence annotation of interferon protein. [PDF]

Comput Struct Biotechnol J
Li B, Yu Y, Ma F, Dong Z, Zhang L.
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Editorial: Novel computational fluid dynamics methods for diagnosis, monitoring, prediction, and personalized treatment for cardiovascular disease and cancer metastasis

Frontiers in Bioengineering and Biotechnology
Zahra Keshavarz Motamed, Nima Maftoon, Lakshmi Prasad Dasi, John F. LaDisa   +3 more
doaj   +1 more source

Assessment of cybersecurity awareness among healthcare professionals. A cross sectional study. [PDF]

J Educ Health Promot
Moothedath M, Abalkhail A, Muhamood M, Ramaiah VV, Mulla M, Mulla M.   +5 more
europepmc   +1 more source

Fundamentals of Computer-Aided Engineering

, 2003
Benny Raphael, Ian F. C. Smith
openalex   +1 more source

Computer-Animated Videos in Education: A Comprehensive Review and Teacher Experiences from Animation Creation [PDF]

Alexandros Kleftodimos
openalex   +1 more source